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0731-88618508
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Lv Ben
Professor, MD, Hematologist, Doctoral Advisor
Awardee of "National Youth Thousand Plan"
EDUCATION
Ph.D Clinical medicine, Xiangya Hospital of Central South University 2007-2010
M.D. Internal Medicine, Xiangya School of Medicine, 2001-2007
ACADEMIC EXPERIENCE
Professor and doctoral tutor, Physician of Department of Hematology, the 3rd xiangya hospital of the Central South University
SOCIAL ACTIVITIES
Assistant Professor at the Feinstein Institute for Medical Research and Hofstra School of Medicine.
Chief Scientist of a National 973 Science Project
RESEARCH AREA
the pathogenesis of sepsis and the molecular mechanisms of inflammation
Contact Me
EMAIL: xybenlv@163.com
RESEARCH PROJECTS
Received several prestigious grants from Chinese government, including the“One thousand people plan”project, “Excellent Young Investigator Science Fund” and a “Natural Science fund” from the Natural Science Foundation of China.
PUBLICATIONS
Published original findings in the prestigious journal Nature, PNAS and Mol Med as both the first author and the co-corresponding author.
1. Lu B *, Nakamura T, Inouye K, Li J, Tang Y, Lundbäck P, I Valdes-Ferrer S, Olofsson PS, Kalb T, Roth J, Zou Y, Erlandsson-Harris H, Yang H, Ting J, Wang H, Andersson U, Antoine DJ, Chavan SS, Hotamisligil GS, Tracey KJ *. Novel role of PKR in inflammasome activation and HMGB1 release. Nature. 2012; 488: 670-4.
2. Lu B *, Antoine DJ, Kwan K, Lundbäck P, Wähämaa H, Schierbeck H, Robinson M, Van Zoelen MA, Yang H, Li J, Harris EH, Chavan SS, Wang H, Andersson U, Tracey KJ *. JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation. Proc Natl Acad Sci U S A. 2014; 111: 3068-73.
3. Lu B *, Kwan K, Levine YA, Olofsson P, Yang H, Li J, Joshi S, Wang H, Andersson U, Chavan SS, Tracey KJ *. Alpha 7 nAchR signaling inhibits inflammasome activation through preventing mitochondrial DNA release. Mol Med. 2014;20:350-358.
4. Lu B, Wang H, Andersson U, Tracey KJ. Regulation of HMGB1 release by inflammasomes. Protein Cell. 2013; 4: 163-7.
5. Lv B, Wang H, Tang Y, Zhang F, Xiao X, Chen F. High mobility group box 1 protein induces tissue factor expression in vascular endothelial cells via activation of NF-κB and Egr-1. Thromb Haemost. 2009; 102: 352-9.