Yang Zuocheng

Professor, MD, Pediatrician,  Doctoral Advisor

EDUCATION

M.D. in Pediatric Cardiology, Hunan Medical University,1986-1990

B. M., in Medicine, Hunan Medical College, 1979-1984

ACADEMIC EXPERIENCE

Professor , the Third Xiangya Hospital, Central South University, 1999-Now

Visiting Scholar, Indiana University School of Medicine, IN, USA, 2000~2003

Associate Professor, the Third Affiliated Hospital, Hunan Medical University, 1993-1999

Attending Doctor, The Third Affiliated Hospital, Hunan Medical University, 1992-1993

Attending Doctor, The Second Affiliated Hospital, Hunan Medical University, 1990-1992

SOCIAL ACTIVITIES

Member of Editorial Board, Chin J Contemp Pedia, Changsha,1999-now

Committee Member, Hunan Pediatrics Association, 1997-now

Committee Member, pediatric branch of China Integrated Chinese and Western Medicine Committee, 2012-now

Research Area

1. Pediatric Cardiology

2. Pediatric Clinical Medicine

Teaching Courses

1. Pediatrics

2. Clinical communication skills

Contact Me

EMAIL: yang_zcr@126.com

PHONE: +86-731-88618517

Research Projects

1. 杨作成，等，2016-2019,氧糖酵解参与柯萨奇病毒B3致心肌炎的机制研究,国家自然科学

2. 杨作成，等，2010-2012,mTOR通路参与柯萨奇B3病毒致病机制研究. 国家自然科学基金

Published Books

1. 杨作成，陈翔主编.,2013, 药品不良反应与合理用药系列丛书:儿科疾病专辑.人民卫生出版社

2. 杨作成 副主编，见：张宝林，等 主编.2010, 中西医临床用药手册. 儿科分册.湖南科学技术出版社

3. 杨作成 副主编，见：叶志中,等 主编. 2009,儿童风湿病学.人民卫生出版社

Published Papers

1. Li Zhong, Weiming Li, Zuocheng Yang (co-first authors), et al. Improved transduction of primary murine hepatocytes by recombinant adeno-associated virus 2 vectors in vivo. Gene Therapy. 2004, 11(14):1165-9.

2.  Li Zhong, Weiming Li, Zuocheng Yang (co-first authors), et al. Impaired Nuclear Transport and Uncoating Limit Recombinant Adeno-associated Virus 2 Vector-Mediated Transduction of Primary Murine Hematopoietic Cells. Human Gene Ther. 2004, 15(12):1207-18.

3. Zuocheng Yang, Irene M. Wolf, Hanying Chen,et al. FKBP52 is Essential to Uterine Reproductive Physiology Controlled By the Progesterone Receptor A Isoform. Mol Endocrinol. 2006, 20(11):2682-94.

4. Yong W, Yang Z (co-first authors), Periyasamy Z, et al. Essential role for Co-chaperone FKBP52 but not FKBP51 in androgen receptor-mediated signaling and physiology. J Biol Chem. 2007; 282(7):5026-36.

5. Liu Z, Dong Z, Yang Z(co-first authors), et al. Role of eIF3a (eIF3 p170) in intestinal cell differentiation and its association with early development. Differentiation. 2007,75(7):652-661

6. Li X, Zhang J, Chen Z, et al. Both PI3K- and mTOR-Signaling Pathways Take Part in CVB3-Induced Apoptosis of HeLa Cells. DNA Cell Biol. 2013, 32(7): 359-370.（通讯作者）

7. Li X, Li Z, Zhou W, et al. Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells. Cell Death Dis. 2013,4, e803; (通讯作者)

8. Chen Z, Yang L, Liu Y, et al. LY294002 and Rapamycin promote coxsackievirus-induced cytopathic effect and apoptosis via inhibition of PI3K/AKT/mTOR signaling pathway. Mol Cell Biochem. 2014, 385(1):169-177 (通讯作者)

9. 杨作成.炎症性心肌病的诊断与治疗.中华实用儿科临床杂志, 2013,28(13):967-969

10. 杨作成.心肌炎的诊断与治疗. 实用儿科临床杂志, 2010;25(10):782-784

11. 杨作成.儿童扩张型心肌病合并心律失常的诊治. 中国实用儿科杂志, 2014,29(9): 654-658

12. 杨作成. 病毒性心肌炎与心肌纤维化. 临床儿科杂志,2007,25(10):807-810

13. 陈淳媛,孙跃女,杨作成*,等. 哺乳类雷帕霉素靶蛋白信号通路对柯萨奇病毒B3诱导的心肌成纤维细胞Smad 3蛋白和Ⅰ型胶原表达调控的实验研究.中华心血管病杂志. 2008, 36(2):156-160

14. 黄麟,杨作成*. 川崎病发病机制的研究进展. 中华儿科杂志. 2009,47(4).265-267

15. 李卓颖, 杨作成*.川崎病患儿内皮素-1及内皮素A、B受体基因多态性研究. 中华风湿病学杂志, 2009,13(11):795-796